
Higher Degrees
The public defense of the master's thesis presented by Ansam Awad Ali Hussein Al-Dalmah, a graduate student in the Department of Biology / College of Education for Women / University of Anbar, was held for her thesis entitled:
"The Effect of Beta-Aminobutyric Acid (BABA) on Liver Damage and Some Immune Parameters in Male Sprague Dawley Rats."
The examination committee consisted of:
Prof. Dr. Mohammed Qais Abd – Chair
Asst. Prof. Dr. Ahmed Qasim Hadi – Member
Asst. Prof. Dr. Nagham Khudair Mahdi – Member
Asst. Prof. Dr. Mohammed Abbas Jassim – Member and Supervisor
The study conducted by the researcher demonstrated the effectiveness of the bioactive compound Beta-Aminobutyric Acid (BABA) in protecting liver tissues and genes from the toxic effects induced by carbon tetrachloride (CCl?).
The results revealed significant differences in liver enzyme levels (AST, ALT) and bilirubin, accompanied by distinct histological changes indicating hepatotoxicity in animals treated with CCl?. In contrast, BABA showed a clear protective and therapeutic role.
Moreover, BABA was found to reduce the gene expression of oxidative stress and genotoxicity markers such as MIP34, MI210, and MI146a.
The study also indicated a significant increase in immune markers (CD4 and CD8) in the treated animals, supporting the hypothesis of BABA’s immunoprotected effect.
Following a thorough scientific discussion by the committee members, the thesis was accepted, and the student was awarded a Pass grade.